Novel traumatic injury model of human brain developed in Kizil Lab

Screen Shot 2019-02-18 at 11.28.47

Our new publication on how #human #neural #stem cells could increase their ability to regenerate lost #neurons after #traumatic #brain #injury in #3D environment is out! Congratulations to all authors!

https://www.frontiersin.org/articles/10.3389/fncel.2019.00023

This work was supported by

About us

The brains of aging humans are prone to neurodegenerative disorders and we are unable to counteract neuronal loss by regenerating lost cells. Patients with neurodegenerative conditions progressively loose neurons yet cannot form new neurons that would replace the lost ones – namely, we humans lack the proper “plasticity response”. We are using zebrafish and novel 3D human culture systems as models to investigate the vertebrate neural stem cells.

Zebrafish regenerates its brain successfully. Our goal is to learn from zebrafish how we can enable the human brain to better cope with neurodegenerative disease and regenerate.

The main motivation of our research group is to understand the molecular programs zebrafish brain uses to induce regenerative stem cell plasticity, and harness this knowledge to unlock the regenerative potential of our brains in Alzheimer’s disease conditions.

Leave a Reply Cancel reply

Enter your comment here...

Fill in your details below or click an icon to log in:

Email (required) (Address never made public)

Name (required)

Website

You are commenting using your WordPress.com account. ( Log Out / Change )

You are commenting using your Facebook account. ( Log Out / Change )

Cancel

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Share this:

Like this:

Related

Leave a Reply Cancel reply