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Cosacak MI, Bhattarai P, Reinhardt S, Petzold A, Dahl A, Zhang Y, Kizil C. Single-Cell Transcriptomics Analyses of Neural Stem Cell Heterogeneity and Contextual Plasticity in a Zebrafish Brain Model of Amyloid Toxicity. Cell Reports. 2019 Apr 23;27(4):1307-1318.e3. doi: 10.1016/j.celrep.2019.03.090. Open access.
Diaz Verdugo C, Myren-Svelstad S, Aydin E, Van Hoeymissen E, Deneubourg C, Vanderhaeghe S, Vancraeynest J, Pelgrims R, Cosacak MI, Muto A, Kizil C, Kawakami K, Jurisch-Yaksi N, Yaksi E. Glia-neuron interactions underlie state transitions to generalized seizures. Nature Communications. 2019 Aug 23;10(1):3830. doi: 10.1038/s41467-019-11739-z. Open access.
Cosacak MI, Bhattarai P, Kizil C. Alzheimer’s disease, neural stem cells and neurogenesis: cellular phase at single-cell level. Neural Regeneration Research. 2020 May;15(5):824-827. doi: 10.4103/1673-5374.268896. Open access.
Celikkaya H, Cosacak MI, Papadimitriou C, Popova S, Bhattarai P, Biswas SN, Siddiqui T, Wistorf S, Nevado-Alcalde I, Naumann L, Mashkaryan V, Brandt K, Freudenberg U, Werner C, Kizil C. (2019) GATA3 Promotes the Neural Progenitor State but Not Neurogenesis in 3D Traumatic Injury Model of Primary Human Cortical Astrocytes. Frontiers in Cellular Neuroscience. 13:23. doi:10.3389/fncel.2019.00023. Open access.
Reinhardt L, Kordes S, Reinhardt P, Glatza M, Baumann M, Drexler HCA, Menninger S, Zischinsky G, Eickhoff J, Fröb C, Bhattarai P, Arulmozhivarman G, Marrone L, Janosch A, Adachi K, Stehling M, Anderson EN, Abo-Rady M, Bickle M, Pandey UB, Reimer MM, Kizil C, Schöler HR, Nussbaumer P, Klebl B, Sterneckert JL. (2019) Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo. Stem Cell Reports. 12(3):502-517. doi: 10.1016/j.stemcr.2019.01.015. Open access.
Kizil C, Bhattarai P. (2018) Is Alzheimer’s Also a Stem Cell Disease? – The Zebrafish Perspective. Frontiers in Cell and Developmental Biology. 6:159. doi:10.3389/fcell.2018.00159. Open Access.
Papadimitriou C, Celikkaya H, Cosacak MI, Mashkaryan V, Bray L, Bhattarai P, Brandt K, Hollak H, Chen X, He S, Antos CL, Lin W, Thomas AK, Dahl A, Kurth T, Friedrichs J, Zhang Y, Freudenberg U, Werner C, Kizil C. (2018) 3D Culture Method for Alzheimer’s Disease Modeling Reveals Interleukin-4 Rescues Aβ42-Induced Loss of Human Neural Stem Cell Plasticity. Developmental Cell. 46(1):85-101.e8. doi: 10.1016/j.devcel.2018.06.005.
Kizil, C. (2018). Mechanisms of pathology-induced neural stem cell plasticity and neural regeneration in adult zebrafish brain. Current Pathobiology Reports. 10.1007/s40139-018-0158-x (PDF)
Cosacak, MI, Yigit, H, Kizil, C, Akgul, B. (2018) Re-Arrangements in the Cytoplasmic Distribution of Small RNAs Following the Maternal-to-Zygotic Transition in Drosophila Embryos. Genes 9:82. 10.3390/genes9020082. (PDF)
Kizil, C. (2018). Turkish Medical Association central council detained for demanding peace. Lancet. PubMed 10.1016/S0140-6736(18)30201-0 (PDF)
Related Editorial (2018). Lancet. (PDF)
Cosacak MI, Bhattarai P, Bocova L, Dzewas T, Mashkaryan V, Papadimitriou C, Brandt K, Hollak H, Antos CL, Kizil C. (2017). Human TAUP301L overexpression results in TAU hyperphosphorylation without neurofibrillary tangles in adult zebrafish brain. Scientific Reports. 7(1), 12959. PubMed 10.1038/s41598-017-13311-5 (PDF)
Bhattarai P, Thomas AK, Mashkaryan V, Cosacak MI, Papadimitriou C, Zhang Y, Kizil C. (2017) Modeling Amyloid-beta42 toxicity and neurodegeneration in adult zebrafish brain. JoVE. 128. PubMed 10.3791/56014
Bhattarai P, Thomas AK, Zhang Y, Kizil C. (2017). The effects of ageing on Amyloid-b42-induced neurodegeneration and regeneration in adult zebrafish brain. Neurogenesis. 4(1):e1322666. PubMed 10.1080/23262133.2017.1322666 (PDF)
Kizil C. (2017) An existential threat. New Scientist. 234(3121):24-25. doi: 1016/S0262-4079(17)30727-3. Link
Bhattarai P, Thomas AK, Cosacak MI, Papadimitriou C, Mashkaryan V, Froc C, Reinhardt S, Kurth T, Dahl A, Zhang Y, Kizil C. (2016) IL4/STAT6 activates neural stem cells in response to Amyloid-b42 aggregation in adult zebrafish brain. Cell Reports, 17(4): 941-948. PubMed 10.1016/j.celrep.2016.09.075 (PDF)
Tincer, G., Mashkaryan, V., Bhattarai, P., Kizil, C. (2016). Neural stem/progenitor cells in Alzheimer’s disease. The Yale Journal of Biology and Medicine, 89(1), 23–35. PubMed
Kizil C. (2016) Degrees of freedom. New Scientist. 231(3084):20-21. doi: 1016/S0262-4079(16)31366-5. Link
Kizil C*, Alberts B, Ayata P, Blobel G, Capecchi M, Clark MM, Curl R, Freiwald WA, Hoffmann R, Mucida D, Nestler EJ, Skotheim JM, Trautmann A, zur Hausen H, Altindis E. (2016). Government: Concern grows for Turkey’s academics. Nature. 529(7587):466. doi: 10.1038/529466a. (*Corresponding author). PubMed
Kizil C*, Kyritsis N, Brand M. (2015) Effects of inflammation on stem cells: together they strive? EMBO Reports. 16(4):416-26. (corresponding author). PubMed 10.15252/embr.201439702
Cosacak MI, Papadimitriou C, Kizil C. (2014). Regeneration, plasticity and induced molecular programs in adult zebrafish brain. BioMed Research International. 2015:769763. PubMed 10.1155/2015/769763
Kizil C, Iltzsche A, Thomas AK, Bhattarai P, Zhang Y, Brand M. (2015) Efficient Cargo Delivery into Adult Brain Tissue Using Short Cell-Penetrating Peptides. PLoS One. 10(4):e0124073. PubMed
Kizil C, Küchler B, Yan JJ, Ozhan G, Moro E, Argenton F, Brand M, Weidinger G, Antos CL. (2014) Simplet/Fam53b is required for Wnt signal transduction by regulating β-catenin nuclear localization. Development. 141(18):3529-39. PubMed
Kyritsis N*, Kizil C*, Brand M. (2014) The role of neuroinflammation in central nervous system regeneration. Trends in Cell Biology. 24(2):128-35 (* equal contribution). PubMed
Kizil C#, Iltzsche A, Kaslin J, Brand M. (2013) Micromanipulation of gene expression in the adult zebrafish brain using cerebroventricular microinjection of morpholino oligonucleotides. JoVE. e50415 (# Corresponding author) PubMed
Altindis E, Alpar MA, Aksay E, Beckwith J, Bökel C, Curl RF, Darnell RB, Elledge SJ, Erman B, Frahm J, Goff SP, Greengard P, Hoffmann R, Ilhan B, Kaslin J, Lipkin SM, Poulopoulou C, Raz E, Rubin MA, Salturk M, Schrock RR, Trautmann A, Unutmaz D, Weinstein H, Kizil C*. (2013) Turkey must end violent response to protests. Science. 341(6143):236. (*Corresponding author) PubMed
Kizil C, Kyritsis N, Dudczig S, Kroehne V, Freudenreich F, Kaslin J, Brand M. (2012) Regenerative neurogenesis from neural progenitor cells requires injury-induced expression of Gata3. Developmental Cell. 23(6): 1230-1237. PubMed
Related Commentary: Strähle U, Schmidt R. (2012) A universal program for tissue regeneration? Developmental Cell. 23(6):1123-4. PubMed
Kyritsis N, Kizil C, Kroehne V, Zocher S, Kaslin J, Freudenreich D, Iltzsche A, Brand M. (2012) Acute inflammation initiates the regenerative response in the adult zebrafish brain. Science. 338(6112): 1353-1356. PubMed
Related commentary: Stella N. (2012) Neuroscience. Inflammation to rebuild a brain. Science. 338(6112):1303-4. PubMed
Related commentary: Cui Y, Li J, Arias-Carrión O, Yuan TF. (2012) Utilizing neuro-inflammation: turning degeneration to regeneration. CNS Neurol Disord Drug Targets. 11(8):953-4. PubMed
Kizil C, Dudczig S, Kyritsis N, Machate A, Blaesche J, Kroehne V, Brand M. (2012). The chemokine receptor cxcr5 regulates the regenerative neurogenesis response in the adult zebrafish brain. Neural Development 7:27. PubMed
Kizil C, Kaslin J, Kroehne V, Brand M. (2012) Adult neurogenesis and brain regeneration in zebrafish. Developmental Neurobiology 72(3):429-461. PubMed
Kizil C, Brand M (2011) Cerebroventricular Microinjection (CVMI) into Adult Zebrafish Brain Is an Efficient Misexpression Method for Forebrain Ventricular Cells. PLoS ONE 6(11): e27395. PubMed
Kizil C. (2011) Academic autonomy: more freedom for Turkish science. Nature. 477(7366):538. PubMed
Kizil C. (2011) Turkish science seeks freedom. Science. 334(6055):452-3. PubMed
Kizil C, Otto GW, Geisler R, Nüsslein-Volhard C, Antos CL. (2009). Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration. Developmental Biology. 325(2):329-40. PubMed
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