Our studies featured in The Scientist

A nice article in The Scientist on the role and promises of adult neurogenesis in Alzheimer's disease. Thanks to Dr. Abby Olena for featuring our previous work in zebrafish and its relationship to decipher how to use adult neurogenesis to tackle Alzheimer's. Reduced Adult Neurogenesis Linked with Alzheimer’s Disease Neural progenitors in a human brain …

Prabesh Bhattarai graduated his PhD

Prabesh Bhattarai successfully defended his PhD thesis and graduated from our lab! Prabesh published 15 papers in respected journals during his PhD with a remarkable record. We wish him all the best for his successful career. Prabesh generated an Alzheimer’s disease model in zebrafish, and identified molecular mechanisms controlling neural stem cell plasticity in experimental …

Mehmet Ilyas Cosacak graduated his PhD

Today is an important and exciting day for our lab. Mehmet Ilyas Cosacak graduated very successfully after defending his PhD thesis that focused on generating neurodegeneration models in zebrafish. He is now a “Dr”. We wholeheartedly congratulate him! His PhD was extraordinary. Ilyas graduated with an outstanding 12 publications. He first authored 5, co-authored 5 …

Our single cell sequencing protocol published in STAR Protocols

We are delighted to share our protocol on how to dissect zebrafish telencephalon for single cell sequencing: https://star-protocols.cell.com/protocols/89 This is based on our original research in Cell Reports in 2019 by Cosacak et al. Cosacak, M.I., Bhattarai, P., Reinhardt, S., Petzold, A., Dahl, A., Zhang, Y., and Kizil, C. (2019). Single-cell transcriptomics analyses of neural stem …

Our new publication: Serotonin orchestrates the neuronal regeneration in Alzheimer’s model of zebrafish brain

We are thrilled to announce our latest paper in PLoS Biology. "Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer’s model of adult zebrafish brain" Our previous research showed that zebrafish is stunning in generating new neurons in response to Alzheimer's disease. But the molecular mechanism underlying was unknown. Here we identified it! By …

World Alzheimer’s Day declaration

Tierversuche Verstehen (an initiative of major research organizations in Germany, such as Max Planck Society, Helmholtz Association, Leibniz Association, DFG, Leopoldina, Fraunhofer Institutes, Alexander von Humboldt Foundation, DAAD, Wissenschaftsrat and others) issued a statement on the future of Alzheimer's disease research. Along with Prof. Chriatian Haass, Prof. Bart De Strooper, Prof. Michael Heneka, Prof. Agnes …