Zebrafish and Alzheimer's Disease
We cordially invite everyone to the 2nd Dresden Dementia Action Day! The information event offers lectures, a variety of information stands and hands-on activities to cover the broad spectrum from basic research to clinical practice to daily living and dealing with people with dementia. Kizil Lab is going to present their work and how a …
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We are happy to announce the publication of our patent as a joint effort of Leibniz Institute of Polymer Research (IPF) and German Center for Neurodegenerative Disease (DZNE). The invention relates to a method for forming a functional network of human neuronal and glial cells, wherein the cells are introduced into a synthetic hydrogel system …
We will present our research in 5th European Zebrafish Principal Investigator Meeting (EZPM) in Trento, Italy between March 20-23, 2018. We will also chair the "Stem Cell Plasticity" workshop. The focus of the workshop will be to discuss how zebrafish stem cells maintain and manifest their capacity for plasticity in various tissues. There will be five …
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We are glad to announce that our PhD student Mr. Prabesh Bhattarai was selected to participate in the Lindau Nobel Laureate Meeting that will be held in June 2018! Lindau Nobel Laureate Meeting is the most prestigious event that brings a highly selected set of scientists in contact with Nobel Laureates and academic partners, and …
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We have published a review article on the current knowledge about the damage-induced molecular programs that underlie the regenerative ability in zebrafish brain in Current Pathobiology Reports. The ability to regenerate lost neurons is one of the aims of designing regenerative therapies in humans. Zebrafish, with its extensive regenerative ability and superb aptitude for …
We are glad to announce our first ever pre-print server publication that documents an innovative 3D system allowing human neural stem cells to produce our brain's various neuronal types and to model Alzheimer's disease with major pathological outcomes replicated outside the brain in a 3D space. With this model, we can study the effects of …
Our research portfolio is growing with valuable support! We are glad to announce that Deutsche Forschungsgemeinschaft approved two research grants to our laboratory for the next two years! We are proud to be trusted by our colleagues and peer reviewers, and will discover more with this important support!
Alzheimer's disease is the most common neurodegenerative disease, and one of the cellular hallmarks is toxicity caused by a protein called TAU. In humans, mutations in TAU leads to disruption of the microtubules, the major transport routes in our neurons. When we lose the integrity of our microtubules, neurons die. A big question is: "Can …
Our video article on generation of an Alzheimer's model in zebrafish brain is out in Journal of Visualized Experiments (JoVE). This has been an excellent collaboration with Yixin Zhang Laboratory in B-Cube at TU Dresden and our laboratory in Deutsches Zentrum für Neurodegenerative Erkrankungen - DZNE and CRTD / DFG Center for Regenerative Therapies at …
We are happy to announce the publication of our work from our lab at Deutsches Zentrum für Neurodegenerative Erkrankungen - DZNE and CRTD / DFG Center for Regenerative Therapies at the TU Dresden on how aging affects the manifestation of Alzheimer's Disease in zebrafish brain. The report will appear this week in the journal …
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