December 6, 2017 by Gwd

Two DFG research grants to Kizil Lab!

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Our research portfolio is growing with valuable support!

We are glad to announce that Deutsche Forschungsgemeinschaft approved two research grants to our laboratory for the next two years! We are proud to be trusted by our colleagues and peer reviewers, and will discover more with this important support!

The brains of aging humans are prone to neurodegenerative disorders and we are unable to counteract neuronal loss by regenerating lost cells. Patients with neurodegenerative conditions progressively loose neurons yet cannot form new neurons that would replace the lost ones – namely, we humans lack the proper “plasticity response”. We are using zebrafish and novel 3D human culture systems as models to investigate the vertebrate neural stem cells.

Zebrafish regenerates its brain successfully. Our goal is to learn from zebrafish how we can enable the human brain to better cope with neurodegenerative disease and regenerate.

The main motivation of our research group is to understand the molecular programs zebrafish brain uses to induce regenerative stem cell plasticity, and harness this knowledge to unlock the regenerative potential of our brains in Alzheimer’s disease conditions.

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