Zebrafish and Alzheimer's Disease
Happy to share our new paper on the non-neuronal / non-motor functions of the spinal locomotor network from Konstantinos Ampatzis Lab. We are glad to be collaborators and contributors to this study published in Nature Communications. https://www.nature.com/articles/s41467-021-25052-1
Smart Biomarkers to Empower Drug Development for Brain Diseases Press release from DZNE: Dresden Researchers Awarded Prestigious Funding by the Helmholtz Association to Validate a Novel Approach that Combines Neuroelectronics and Artificial Intelligence i3D-Markers project page:
A nice article in The Scientist on the role and promises of adult neurogenesis in Alzheimer's disease. Thanks to Dr. Abby Olena for featuring our previous work in zebrafish and its relationship to decipher how to use adult neurogenesis to tackle Alzheimer's. Reduced Adult Neurogenesis Linked with Alzheimer’s Disease Neural progenitors in a human brain …
Prabesh Bhattarai successfully defended his PhD thesis and graduated from our lab! Prabesh published 15 papers in respected journals during his PhD with a remarkable record. We wish him all the best for his successful career. Prabesh generated an Alzheimer’s disease model in zebrafish, and identified molecular mechanisms controlling neural stem cell plasticity in experimental …
Today is an important and exciting day for our lab. Mehmet Ilyas Cosacak graduated very successfully after defending his PhD thesis that focused on generating neurodegeneration models in zebrafish. He is now a “Dr”. We wholeheartedly congratulate him! His PhD was extraordinary. Ilyas graduated with an outstanding 12 publications. He first authored 5, co-authored 5 …
We are glad to be part of this amazing story published today in Science Advances, where functional ramifications of sequential neurogenesis in zebrafish habenula was published by Emre Yaksi Lab in NTNU, Norway. Congrats to all authors! https://advances.sciencemag.org/content/6/36/eaaz3173
Our open-access review on the comparative aspects of glia in zebrafish and mammals is out at Glia. Big thanks to our institutes and funding agencies for their support. https://doi.org/10.1002/glia.23849
We are delighted to share our protocol on how to dissect zebrafish telencephalon for single cell sequencing: https://star-protocols.cell.com/protocols/89 This is based on our original research in Cell Reports in 2019 by Cosacak et al. Cosacak, M.I., Bhattarai, P., Reinhardt, S., Petzold, A., Dahl, A., Zhang, Y., and Kizil, C. (2019). Single-cell transcriptomics analyses of neural stem …
Continue reading "Our single cell sequencing protocol published in STAR Protocols"
Our work spotlighted by DZNE: https://www.dzne.de/en/spotlight/meldungen/2020/growing-new-neurons-learning-from-the-fish/
We are thrilled to announce our latest paper in PLoS Biology. "Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer’s model of adult zebrafish brain" Our previous research showed that zebrafish is stunning in generating new neurons in response to Alzheimer's disease. But the molecular mechanism underlying was unknown. Here we identified it! By …
