Our publication was featured on MDR, German national TV news.
We generated an Amyloid-beta42 toxicity model in adult zebrafish brain
We are happy to announce an advance we achieved in #Alzheimer's research here at our lab. We generated an Amyloid-β42 toxicity model in adult #zebrafish #brain, which shows cell death, microglial activation, synaptic degeneration and learning deficits. Unlike humans, fish brain increase stem cell proliferation and neurogenesis upon Aβ42. We found that Interleukin-4 as a …
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Neural stem cells in Alzheimer’s disease
Alzheimer’s disease is the most prevalent neurodegenerative disease and a worldwide health challenge. Different therapeutic approaches are being developed to revert or slow the loss of affected neurons. Alternatively, we also need to mobilize the existing neural stem/progenitor cells (NSPCs) to regenerate lost neurons despite the existing pathology and unfavorable environment. We need to induce …
