The progressive, age related degeneration of the structure and function of proteins and cells in the nervous system can lead to issues involving memory and motor function loss. Join us to gain insights into recent advances in this field of neuroscience. https://go.myabcam.com/webinar-neurodegenerative-diseases-2021?_ga=2.122838339.99911988.1665094521-1263913016.1665094521
We identified a new signaling pathway that controls pathology-induced neural stem cell plasticity in zebrafish brain
We show a new signaling mechanism through Kynurenic acid and Aryl hydrocarbon receptor in regulating the proliferation of a specific subset of neural stem cells in adult #zebrafish model of #Alzheimer's disease. https://www.mdpi.com/2073-4409/10/10/2748
Locomotion dependent neuron-glia interactions control neurogenesis and regeneration in the adult zebrafish spinal cord
Happy to share our new paper on the non-neuronal / non-motor functions of the spinal locomotor network from Konstantinos Ampatzis Lab. We are glad to be collaborators and contributors to this study published in Nature Communications. https://www.nature.com/articles/s41467-021-25052-1
We received the Helmholtz President’s Initiative Funds – Helmholtz Validation funds for i3D-Markers
Smart Biomarkers to Empower Drug Development for Brain Diseases Press release from DZNE: Dresden Researchers Awarded Prestigious Funding by the Helmholtz Association to Validate a Novel Approach that Combines Neuroelectronics and Artificial Intelligence i3D-Markers project page:
Our studies featured in The Scientist
A nice article in The Scientist on the role and promises of adult neurogenesis in Alzheimer's disease. Thanks to Dr. Abby Olena for featuring our previous work in zebrafish and its relationship to decipher how to use adult neurogenesis to tackle Alzheimer's. Reduced Adult Neurogenesis Linked with Alzheimer’s Disease Neural progenitors in a human brain …
Prabesh Bhattarai graduated his PhD
Prabesh Bhattarai successfully defended his PhD thesis and graduated from our lab! Prabesh published 15 papers in respected journals during his PhD with a remarkable record. We wish him all the best for his successful career. Prabesh generated an Alzheimer’s disease model in zebrafish, and identified molecular mechanisms controlling neural stem cell plasticity in experimental …
Mehmet Ilyas Cosacak graduated his PhD
Today is an important and exciting day for our lab. Mehmet Ilyas Cosacak graduated very successfully after defending his PhD thesis that focused on generating neurodegeneration models in zebrafish. He is now a “Dr”. We wholeheartedly congratulate him! His PhD was extraordinary. Ilyas graduated with an outstanding 12 publications. He first authored 5, co-authored 5 …
Collaborative publication in Science Advances
We are glad to be part of this amazing story published today in Science Advances, where functional ramifications of sequential neurogenesis in zebrafish habenula was published by Emre Yaksi Lab in NTNU, Norway. Congrats to all authors! https://advances.sciencemag.org/content/6/36/eaaz3173
Our new review published in Glia
Our open-access review on the comparative aspects of glia in zebrafish and mammals is out at Glia. Big thanks to our institutes and funding agencies for their support. https://doi.org/10.1002/glia.23849
Our single cell sequencing protocol published in STAR Protocols
We are delighted to share our protocol on how to dissect zebrafish telencephalon for single cell sequencing: https://star-protocols.cell.com/protocols/89 This is based on our original research in Cell Reports in 2019 by Cosacak et al. Cosacak, M.I., Bhattarai, P., Reinhardt, S., Petzold, A., Dahl, A., Zhang, Y., and Kizil, C. (2019). Single-cell transcriptomics analyses of neural stem …
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Kizil Lab 