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Neural Stem Cells, Alzheimer's Disease and Regeneration

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Tag: regeneration

Posted on January 21, 2020January 21, 2020

DZNE spotlight on our publication

Our work spotlighted by DZNE: https://www.dzne.de/en/spotlight/meldungen/2020/growing-new-neurons-learning-from-the-fish/

About us

The brains of aging humans are prone to neurodegenerative disorders and we are unable to counteract neuronal loss by regenerating lost cells. Patients with neurodegenerative conditions progressively loose neurons yet cannot form new neurons that would replace the lost ones – namely, we humans lack the proper “plasticity response”. We are using zebrafish and novel 3D human culture systems as models to investigate the vertebrate neural stem cells.

Zebrafish regenerates its brain successfully. Our goal is to learn from zebrafish how we can enable the  human brain to better cope with neurodegenerative disease and regenerate.

The main motivation of our research group is to understand the molecular programs zebrafish brain uses to induce regenerative stem cell plasticity, and harness this knowledge to unlock the regenerative potential of our brains in Alzheimer’s disease conditions.

 

 

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The institutes Kizil lab is affiliated with had no association with this website nor they can be liable for the content. This website and its contents may not reflect the opinions of the affiliated institutes.

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