Zebrafish and Alzheimer's Disease
We are excited to share a collaborative study, published in Cell Reports: "Topoisomerase I inhibition yields a CD74high/MHChigh human microglial subtype with enhanced Aβ uptake" (Haage et al., 2026). Congratulations to all authors, and especially to first author Verena Haage and senior author Philip De Jager for leading this effort. Thanks as well to our …
Continue reading "Recreating a human microglial state with a drug: new publication in Cell Reports"
Our lab's research on the earliest biological drivers of Alzheimer's years before symptoms appear was featured on PIX11 this morning. Our work centers on the earliest mechanisms driving Alzheimer's risk — specifically, how breakdown of the blood-brain barrier and neuroinflammation set the stage for disease years before symptoms emerge. We believe this early window is …
The Kizil Lab is pleased to participate in the European Zebrafish Meeting (EZM 2026) in Vienna, Austria. During the meeting, we presented our latest research, engaged in stimulating discussions with colleagues from across the international zebrafish community, and had the privilege of chairing sessions on disease models. The conference once again highlighted the remarkable versatility …
Continue reading "Kizil Lab at European Zebrafish Meeting 2026"
Our associate research scientist, Dr. Prabesh Bhattarai, was recently featured on the Research Renaissance podcast, where he spoke with host Deborah Westphal about how regenerative biology could open new doors for Alzheimer's treatment. Dr. Bhattarai discussed how zebrafish are able to regenerate neurons lost to Alzheimer's-like damage and why humans and mice can't do the …
Our lab presented our findings ranging from zebrafish to human brains in AD/PD™ 2025 Alzheimer's & Parkinson's Diseases Conference in Vienna by Dr. Elanur Yilmaz and Dr. Prabesh Bhattarai and in 7th European Zebrafish Principal Investigators Meeting in Paris by Dr. Caghan Kizil.
On November 13, 2023, benefactors, faculty, and friends from the Columbia University Vagelos College of Physicians and Surgeons (VP&S) community joined together to celebrate the 14th Annual Crown Awards Gala at The Glasshouse in New York City. The evening celebrated how Columbia’s philanthropic partners, faculty, students, and staff are “Transforming Health by Driving Discovery.” We are …
Prabesh Bhattarai successfully defended his PhD thesis and graduated from our lab! Prabesh published 15 papers in respected journals during his PhD with a remarkable record. We wish him all the best for his successful career. Prabesh generated an Alzheimer’s disease model in zebrafish, and identified molecular mechanisms controlling neural stem cell plasticity in experimental …
DZNE held an Open Day on June 30, 2019. We participated and felt the joy of interacting with public and tell them the amazing work done in DZNE as a whole! Congratulations to all!
We attended the conference in beautiful Suzhou, China, where more than 1,200 zebrafish researchers gathered together to discuss their latest research. We chaired the "Disease Models and Mechanisms" session and presented our work. https://www.izfs.org/page/2019IZFC
We participated in the conference where zebrafish researchers around the world presented their work. Kizil lab chaired the "Disease models and Mechanisms" session. https://www.izfs.org/page/2019IZFC
