Zebrafish and Alzheimer's Disease
On May 10, 2017, Deutsches Zentrum für Neurodegenerative Erkrankungen - DZNE, CRTD / DFG Center for Regenerative Therapies at the TU Dresden, TU Dresden, Universitätsklinikum Carl Gustav Carus Dresden and Volkshochschule Dresden e.V. are organizing a joint event: Dresden Demetia Day for the first time. Our lab will be giving a public evening lecture organized …
Continue reading "We participate in the 1st Dementia Action Day in Dresden"
Our study was covered in Sachsen Fernsehen
Our publication was featured on MDR, German national TV news.
We are happy to announce an advance we achieved in #Alzheimer's research here at our lab. We generated an Amyloid-β42 toxicity model in adult #zebrafish #brain, which shows cell death, microglial activation, synaptic degeneration and learning deficits. Unlike humans, fish brain increase stem cell proliferation and neurogenesis upon Aβ42. We found that Interleukin-4 as a …
Continue reading "We generated an Amyloid-beta42 toxicity model in adult zebrafish brain"
Alzheimer’s disease is the most prevalent neurodegenerative disease and a worldwide health challenge. Different therapeutic approaches are being developed to revert or slow the loss of affected neurons. Alternatively, we also need to mobilize the existing neural stem/progenitor cells (NSPCs) to regenerate lost neurons despite the existing pathology and unfavorable environment. We need to induce …
Kizil Lab 